This needs DaVinci Resolve Studio on an Apple Silicon Mac. The free version does not load OpenFX plugins from other vendors, and the plugin itself is arm64 only because Resolve loads it into its own process. On an Intel Mac, use Premiere Pro or SDI IN instead.
Install the plugin
Install the Resolve plugin under Settings → Plugin Sources, then quit Resolve and start it again so it picks the plugin up.Add the effect to the timeline node
The Color page has two node levels. Clip works on the shot under the playhead, Timeline works on the finished programme. You want Timeline, otherwise the stream only carries the one shot you happened to be on.1
Open the Color page
Switch to the Color page and open the Library panel on the right, where the OpenFX effects live.

2
Switch the node graph to Timeline
Above the node graph, change the mode from Clip to Timeline. Then type 
dfine into the library search. dfine.io Transmit appears.
3
Drag it into the node graph
Pull dfine.io Transmit from the library into the empty node graph.

4
Switch on Transmit Audio
With the node selected, open its settings on the right. Tick Transmit Audio. It is off by default, and this is the only step audio needs: no Fairlight, no second plugin.
